SECTION 1. CHEMICAL IDENTIFICATION
PRODUCT #:	AT104
NAME:	ACCUTASE - STERILE 100ml
COMMON SYNONYMS:	ENZYME CELL DETACHMENT MEDIUM
CHEMICAL FAMILY:	CELL CULTURE MEDIUM PRODUCTS
FORMULA:	N/A
FORMULA WT.:	N/A
PRODUCT USE:	FOR RESEARCH ONLY AS CELL CULTURE ADHERENT CELL DETACHMENT ADDITIVE

SECTION 2. COMPOSITION/INFORMATION ON INGREDIENTS
CAS NO.:	N/A
NIOSH/RTECS NO.:	N/A
COMPOSITION:	PROPRIETARY FORMULATION OF ENZYMES, WATER, PHOSPHATE BUFFERED SALINE, PHENOL RED

SECTION 3. HAZARDS IDENTIFICATION
LABEL PRECAUTIONARY STATEMENTS	CAUTION: THE CHEMICAL PHYSICAL AND TOXICOLOGICAL PROPERTIES OF THIS PRODUCT HAVE NOT BEEN THOROUGHLY INVESTIGATED. NON-TOXIC TO CELLS IN CULTURE AT DILUTED CONCENTRATION OF PRODUCT. EXERCISE DUE CARE..
ESTIMATED RISK ASSESSMENT	HEALTH 1 SLIGHT FLAMMABILITY 1 SLIGHT REACTIVITY 1 SLIGHT CONTACT 1 SLIGHT
LABORATORY PROTECTIVE EQUIPMENT	GOGGLES OR VENTED HOOD; LAB COAT; PROPER GLOVES
U.S. PRECAUTIONARY LABELING	CAUTION: MAY BE HARMFUL IF INHALED OR SWALLOWED. MAY CAUSE IRRITATION. THIS PRODUCT IS NOT ON THE TSCA INVENTORY. AVOID CONTACT WITH EYES, SKIN, CLOTHING. USE WITH ADEQUATE VENTILATION. WASH AFTER HANDLING.
INTERNATIONAL LABELING	AVOID CONTACT WITH EYES. AFTER CONTACT WITH SKIN, WASH IMMEDIATELY WITH PLENTY OF WATER. KEEP CONTAINER TIGHTLY CLOSED.

SECTION 4. FIRST AID MEASURES
FIRST AID MEASURES	IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. REMOVE CONTAMINATED SHOES OR CLOTHING. IF INHAHALED, REMOVE TO FRESH AIR. IF NOT BREATHING, GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE REUSE.

SECTION 5. FIRE FIGHTING MEASURES
FLASH POINT (CLOSED CUP):	N/A
AUTOIGNITION TEMPERATURE:	N/A
FLAMMABLE LIMITS:	UPPER - N/A LOWER - N/A
EXTINGUISHING MEDIA	WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIRE FIGHTING PROCEDURES	WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH EYES AND SKIN.
UNUSUAL FIRE AND EXPLOSION HAZARDS	NONE IDENTIFIED
TOXIC GASES PRODUCED	EMITS CARBON DIOXIDE AND CARBON MONOXIDE.
EXPLOSION DATA	SENSITIVITY TO MECHANICAL IMPACT OR STATIC DISCHARGE - NONE IDENTIFIED

SECTION 6. ACCIDENTAL RELEASE MEASURES
ACCIDENTAL RELEASE MEASURES	WEAR RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER GLOVES. ABSORB ON SAND OR VERMICULITE AND PLACE IN CLOSED CONTAINERS FOR DISPOSAL. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICK-UP IS COMPLETE.

SECTION 7. HANDLING AND STORAGE
HANDLING AND STORAGE	KEEP CONTAINER TIGHTLY CLOSED WHEN NOT IN USE. SUITABLE FOR ANY GENERAL CHEMICAL STORAGE AREA, REFRIGERATED OR NON-REFRIGERATED. HANDLE WITH STERILE OR ASEPTIC TECHNIQUE.

SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
EXPOSURE CONTROLS/ PERSONAL PROTECTION	REFER TO SECTION 7.

SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
BOILING POINT:	N/D VAPOR PRESSURE (MMHG): < 1
MELTING POINT:	N/D VAPOR DENSITY (AIR = 1): N/D
SPECIFIC GRAVITY:	1.2 EVAPORATION RATE : N/D (H2O = 1)
SOLUBILITY (H2O):	APPRECIABLE (100%) % VOLATILES BY VOLUME: -0- (21 C)
PH:	7.0-7.5 ODOR THRESHHOLD (PPM): N/D
PHYSICAL STATE:	LIQUID WATER/OIL DISTRIBUTION: N/D
APPEARANCE & ODOR:	PALE RED CLEAR LIQUID, NO CHARACTERISTIC ODOR.

SECTION 10. STABILITY AND REACTIVITY
STABILITY:	STABLE UNDER NORMAL TEMPERATURES AND PRESSURES.
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS TOXIC FUMES OF:	NONE IDENTIFIED
	HAZARDOUS POLYMERIZATION WILL NOT OCCUR.

SECTION 11. TOXICOLOGICAL INFORMATION
THRESHHOLD LIMIT VALUE (TLV/TWA):	NOT ESTABLISHED
SHORT TERM EXPOSURE LIMIT (STEL):	NOT ESTABLISHED
PERMISSIBLE EXPOSURE LIMIT (PEL):	NOT ESTABLISHED
TOXICITY OF COMPONENTS	INTRAPERITONEAL RAT LD 50 FOR ACCUTASE NOT DETERMINED
CARCINO- GENICITY:	NTP: NO IARC: NO Z LIST: NO OSHA REG: NO
CARCINO- GENICITY:	NONE IDENTIFIED.
REPRODUCTIVE EFFECTS:	NOT DETERMINED.
EFFECTS OF OVER EXPOSURE:	MAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN ABSORPTION. MAY CAUSE IRRITATION. THE TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
CHRONIC EFFECTS:	NONE IDENTIFIED.
TARGET ORGANS:	EYES, SKIN, MUCOUS MEMBRANES
MEDICAL CONDITIONS GENERALLY AGGRAVATED BY EXPOSURE:	NONE IDENTIFIED.
PRIMARY ROUTES OF ENTRY:	INHALATION, EYE CONTACT, SKIN CONTACT.
SARA/TITLE III HAZARD CATEGORIES AND LISTS:	ACUTE: YES CHRONIC: YES FLAMMABILITY: NO PRESSURE: NO REACTIVITY: NO
EXTREMELY HAZARDOUS SUBSTANCE:	NO
CERCLA HAZARDOUS SUBSTANCE:	NO
SARA 313 TOXIC CHEMICALS:	NO
TSCA INVENTORY:	NO

SECTION 12. ECOLOGICAL INFORMATION
ECOLOGICAL INFORMATION	DATA NOT YET AVAILABLE

SECTION 13. DISPOSAL CONSIDERATIONS
DISPOSAL PROCEDURES:	DISPOSE IN ACCORDANCE WITH ALL APPLICABLE FEDERAL, STATE, AND LOCAL ENVIRONMENTAL REGULATIONS.

SECTION 14. TRANSPORT INFORMATION
DOMESTIC (D.O.T.) PROPER SHIPPING NAME:	CHEMICALS, N.O.S. (NON-REGULATED)
INTERNATIONAL (I.M.O.) PROPER SHIPPING NAME:	CHEMICALS, N.O.S. (NON-REGULATED)
MARINE POLLUTANTS:	NO
AIR (I.C.A.O.) PROPER SHIPPING NAME	CHEMICALS, N.O.S. (NON-REGULATED)
U.S. CUSTOMS HARMONIZATION CODE NUMBER:	3507.9.0000

SECTION15. REGULATORY INFORMATION
REVIEWS, STANDARDS AND REGULATIONS:	DATA NOT YET AVAILABLE.

SECTION 16. OTHER INFORMATION
ABBREVIATIONS	N/A = NOT AVAILABLE OR NOT APPLICABLE N/D = NOT DETERMINED
	THE INFORMATION IN THIS MATERIAL SAFETY DATA SHEET MEETS THE REQUIREMENTS OF THE UNITED STATES OCCUPATIONAL SAFETY AND HEALTH ACT AND REGULATIONS PROMULGATED THEREUNDER (29 CFR 1910.1200 ET. SEQ.) AND THE CANADIAN WORKPLACE HAZARDOUS MATERIALS INFORMATION SYSTEM. THE INFORMATION ABOVE IS BELIEVED TO BE ACCURATE AND REPRESENTS THE BEST INFORMATION CURRENTLY AVAILABLE TO US. THIS DOCUMENT IS INTENDED ONLY AS A GUIDE TO THE APPROPRIATE PRE CAUTIONARY HANDLING OF THE MATERIAL BY A PERSON TRAINED IN OR SUPERVISED BY A PERSON TRAINED IN CHEMICAL HANDLING AND CELL CULTURE. THE USER IS RESPONSIBLE FOR DETERMINING THE PRECAUTIONS AND DANGERS OF THIS CHEMICAL FOR HIS OR HER PARTICULAR APPLICATION. DEPENDING ON USAGE, PROTECTIVE CLOTHING INCLUDE EYE AND FACE GUARDS AND RESPIRATORS MUST BE USED TO AVOID CONTACT WITH MATERIAL OR BREATHING CHEMICAL FUMES/VAPORS.EXPOSURE TO THIS PRODUCT MAY HAVE SERIOUS ADVERSE HEALTH EFFECTS. THIS CHEMICAL MAY INTERACT WITH OTHER SUBSTANCES. INNOVATIVE CELL TECHNOLOGIES CANNOT WARN OF ALL OF THE POTENTIAL DANGERS OF USE OR INTERACTION WITH OTHER CHEMICALS OR MATERIALS. INNOVATIVE CELL TECHNOLOGIES, INC. WARRENTS THAT THE CHEMICAL MEETS THE SPECIFICATIONS SET FORTH ON THE LABEL. INNOVATIVE CELL TECHNOLOGIES, INC. DISCLAIMS ANY OTHER WARRANTIES, EXPRESSED OR IMPLIED WITH REGARD TO THE PRODUCT SUPPLIED HEREUNDER, ITS MERCHANTABILITY OR ITS FITNESS FOR A PARTICULAR PURPOSE. AS NEW DOCUMENTED GENERAL SAFETY INFORMATION BECOMES AVAILABLE, INNOVATIVE CELL TECHNOLOGIES, INC. WILL PERIODICALLY REVISE THIS MATERIAL SAFETY DATA SHEET. NOTE: THE NATIONAL RESPONSE CENTER EMERGENCY TELEPHONE NUMBER IS TO BE USED ONLY IN THE EVENT OF CHEMICAL EMERGENCIES INVOLVING A SPILL, LEAK, FIRE, EXPOSURE,OR ACCIDENT INVOLVING CHEMICALS. ALL NON-EMERGENCY QUESTIONS SHOULD BE DIRECTED TO INNOVATIVE CELL TECHNOLOGIES CUSTOMER SERVICE FOR ASSISTANCE (+619 223 5551). COPYRIGHT 1996 INNOVATIVE CELL TECHNOLOGIES, INC. ACCUTASE IS A TRADEMARK OF INNOVATIVE CELL TECHNOLOGIES. APPROVED BY ICT/INC QUALITY ASSURANCE DEPARTMENT. FILE: MSWDISKA\MSDSMM.DOC REV.1/9606 PRPD BY DOCPREP SERVICES 1996